Mapping the geographical distribution of the mucosa-associated gut microbiome in GI-symptomatic children with autism spectrum disorder

2024/06/18 by Kimberly D. Reeves, Yosauri F. Figuereo, Victoria G. Weis +5
Biochemistry, Genetics and Molecular Biology · Health Professions · Psychology · #Family and Disability Support Research #Gut microbiota and health #Pediatric health and respiratory diseases

paper · doi:10.1152/ajpgi.00101.2024

openalex publication_date 2024/06/18 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/03

Abstract

Analysis in stool samples has shown gut microbiota alterations in children with autism spectrum disorder (ASD) compared with typically developing (TD) children. However, it is unclear which segment(s) of the gut exhibit alterations in microbiome composition. In this study, we examined microbiota composition along the gastrointestinal (GI) tract in the stomach, duodenum, ileum, right colon, and rectum. We found site-specific and sex-specific differences in the gut microbiota of children with ASD, compared with controls.

Citations

• The SILVA ribosomal RNA gene database project: improved data processing and web-based tools
• Food Selectivity and Sensory Sensitivity in Children with Autism Spectrum Disorders
• Role of Gut Microbiome in Autism Spectrum Disorder and Its Therapeutic Regulation

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