Light intensity alters the effects of light-induced circadian disruption on glucose and lipid metabolism in mice

2021/11/01 by Xiaojing Fan, Defu Chen, Ying Wang +8 · 1 citation
Medicine · Neuroscience · #Adipose Tissue and Metabolism #Circadian rhythm and melatonin #Dietary Effects on Health

paper · doi:10.1152/ajpendo.00025.2021

openalex publication_date 2021/11/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

Glucose and lipid homeostasis is altered by the CD cycles in a light-intensity-dependent manner. Lower-intensity light reverses the negative metabolic effects of the CD cycles, especially under HFD feeding. The interaction of light intensity and light cycle on metabolism is independent of energy intake and eating pattern. Glucose metabolic disorders caused by rotating light cycles occur along with compensatory β-cell mass expansion.

Citations

• Circadian regulation of glucose, lipid, and energy metabolism in humans

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