2024/05/16 by Jennifer H. McQuiston, Richard Luce, Dieudonne Mwamba Kazadi +40 · 3 citations
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · #Bacillus and Francisella bacterial research #Poxvirus research and outbreaks #Yersinia bacterium, plague, ectoparasites research
paper · pdf · doi:10.15585/mmwr.mm7319a3
openalex publication_date 2024/05/16 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01
Clade I monkeypox virus (MPXV), which can cause severe illness in more people than clade II MPXVs, is endemic in the Democratic Republic of the Congo (DRC), but the country has experienced an increase in suspected cases during 2023-2024. In light of the 2022 global outbreak of clade II mpox, the increase in suspected clade I cases in DRC raises concerns that the virus could spread to other countries and underscores the importance of coordinated, urgent global action to support DRC's efforts to contain the virus. To date, no cases of clade I mpox have been detected outside of countries in Central Africa where the virus is endemic. CDC and other partners are working to support DRC's response. In addition, CDC is enhancing U.S. preparedness by raising awareness, strengthening surveillance, expanding diagnostic testing capacity for clade I MPXV, ensuring appropriate specimen handling and waste management, emphasizing the importance of appropriate medical treatment, and communicating guidance on the recommended contact tracing, containment, behavior modification, and vaccination strategies.