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More powerful logrank permutation tests for two-sample survival data

2018/07/15 by Ditzhaus, Marc, Friedrich, Sarah · 1 citation
#FOS: Mathematics #Statistics Theory (math.ST)

paper · doi:10.48550/arxiv.1807.05504

Abstract

Weighted logrank tests are a popular tool for analyzing right censored survival data from two independent samples. Each of these tests is optimal against a certain hazard alternative, for example the classical logrank test for proportional hazards. But which weight function should be used in practical applications? We address this question by a flexible combination idea leading to a testing procedure with broader power. Beside the test's asymptotic exactness and consistency its power behaviour under local alternatives is derived. All theoretical properties can be transferred to a permutation version of the test, which is even finitely exact under exchangeability and showed a better finite sample performance in our simulation study. The procedure is illustrated in a real data example.

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