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Quantum Machine Learning for Material Synthesis and Hardware Security

2022/08/16 by Collin Beaudoin, Satwik Kundu, Beaudoin, Collin +5
Computer Science · Engineering · #Advanced Memory and Neural Computing #FOS: Computer and information sciences #FOS: Physical sciences #Integrated Circuits and Semiconductor Failure Analysis #Machine Learning (cs.LG) #Physical Unclonable Functions (PUFs) and Hardware Security #Quantum Physics (quant-ph)

paper · pdf · doi:10.48550/arxiv.2208.08273

openalex publication_date 2022/08/16 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

Using quantum computing, this paper addresses two scientifically pressing and day-to-day relevant problems, namely, chemical retrosynthesis which is an important step in drug/material discovery and security of the semiconductor supply chain. We show that Quantum Long Short-Term Memory (QLSTM) is a viable tool for retrosynthesis. We achieve 65% training accuracy with QLSTM, whereas classical LSTM can achieve 100%. However, in testing, we achieve 80% accuracy with the QLSTM while classical LSTM peaks at only 70% accuracy! We also demonstrate an application of Quantum Neural Network (QNN) in the hardware security domain, specifically in Hardware Trojan (HT) detection using a set of power and area Trojan features. The QNN model achieves detection accuracy as high as 97.27%.

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