The mRNA Binding Proteins HuR and Tristetraprolin Regulate Cyclooxygenase 2 Expression During Colon Carcinogenesis

2009/01/16 by Lisa E. Young, Lisa Young, Sandhya Sanduja +5 · 27 citations
Biochemistry, Genetics and Molecular Biology · #RNA Research and Splicing #Cancer-related molecular mechanisms research #MicroRNA in disease regulation

paper · doi:10.1053/j.gastro.2009.01.010

Cited by

• Posttranscriptional control of the chemokine receptor CXCR4 expression in cancer cells
• RNA‐Binding Proteins and Ferroptosis in Cancer: Mechanism and Therapeutic Implications
• The role of COX-2 in intestinal inflammation and colorectal cancer. [europepmc]
• The RNA-binding zinc-finger protein tristetraprolin regulates AU-rich mRNAs involved in breast cancer-related processes. [europepmc]
• The roles of TTP and BRF proteins in regulated mRNA decay. [europepmc]
• Tristetraprolin regulates interleukin-6, which is correlated with tumor progression in patients with head and neck squamous cell carcinoma. [europepmc]
• Posttranscriptional regulation of cancer traits by HuR. [europepmc]
• The mRNA stability factor HuR inhibits microRNA-16 targeting of COX-2. [europepmc]
• Myeloid cell expression of the RNA-binding protein HuR protects mice from pathologic inflammation and colorectal carcinogenesis. [europepmc]
• The role of tristetraprolin in cancer and inflammation. [europepmc]
• HuR function in disease. [europepmc]
• LincRNA-p21 suppresses target mRNA translation. [europepmc]
• Mechanistic aspects of COX-2 expression in colorectal neoplasia. [europepmc]
• Tristetraprolin (TTP): interactions with mRNA and proteins, and current thoughts on mechanisms of action. [europepmc]
• Pharmacological inhibition of platelet-tumor cell cross-talk prevents platelet-induced overexpression of cyclooxygenase-2 in HT29 human colon carcinoma cells. [europepmc]
• Identification and validation of novel small molecule disruptors of HuR-mRNA interaction. [europepmc]
• Translating the Untranslated Region. [europepmc]
• The mRNA-binding protein HuR promotes hypoxia-induced chemoresistance through posttranscriptional regulation of the proto-oncogene PIM1 in pancreatic cancer cells. [europepmc]
• Regulatory consequences of neuronal ELAV-like protein binding to coding and non-coding RNAs in human brain. [europepmc]
• The control of inflammation via the phosphorylation and dephosphorylation of tristetraprolin: a tale of two phosphatases. [europepmc]
• HuR Small-Molecule Inhibitor Elicits Differential Effects in Adenomatosis Polyposis and Colorectal Carcinogenesis. [europepmc]
• Posttranscriptional Regulation of PARG mRNA by HuR Facilitates DNA Repair and Resistance to PARP Inhibitors. [europepmc]
• The Jun/miR-22/HuR regulatory axis contributes to tumourigenesis in colorectal cancer. [europepmc]
• RNA Binding Proteins in Intestinal Epithelial Biology and Colorectal Cancer. [europepmc]
• Interaction between HuR and circPABPN1 Modulates Autophagy in the Intestinal Epithelium by Altering ATG16L1 Translation. [europepmc]
• Exosomal circSHKBP1 promotes gastric cancer progression via regulating the miR-582-3p/HUR/VEGF axis and suppressing HSP90 degradation. [europepmc]
• Circular RNA circRHOBTB3 represses metastasis by regulating the HuR-mediated mRNA stability of PTBP1 in colorectal cancer. [europepmc]