In Vitro-Derived Alternatively Activated Macrophages Reduce Colonic Inflammation in Mice

2010/01/05 by Meaghan M. Hunter, Arthur Wang, Kuljit S. Parhar +6 · 31 citations
Immunology and Microbiology · #Immune cells in cancer #Neutrophil, Myeloperoxidase and Oxidative Mechanisms #Parasites and Host Interactions

paper · doi:10.1053/j.gastro.2009.12.041

Cited by

• VEGF-C–dependent stimulation of lymphatic function ameliorates experimental inflammatory bowel disease
• GPx1 deficiency confers increased susceptibility to ferroptosis in macrophages from individuals with active Crohn’s disease
• High-dimensional single-cell mass cytometry analysis of IL-4 treated human macrophages reveals heterogeneity and a CD206high anticolitic subset
• Omega-6 docosapentaenoic acid-derived resolvins and 17-hydroxydocosahexaenoic acid modulate macrophage function and alleviate experimental colitis
• Colonic macrophage polarization in homeostasis, inflammation, and cancer
• Calcitonin gene-related peptide promotes epithelial reparative and anticolitic functions of IL-4 educated human macrophages
• Human gingiva-derived mesenchymal stem cells elicit polarization of m2 macrophages and enhance cutaneous wound healing. [europepmc]
• Alternative activation of macrophages by IL-4 requires SHIP degradation. [europepmc]
• Classically and alternatively activated bone marrow derived macrophages differ in cytoskeletal functions and migration towards specific CNS cell types. [europepmc]
• CX3CR1 regulates intestinal macrophage homeostasis, bacterial translocation, and colitogenic Th17 responses in mice. [europepmc]
• Helminth-host immunological interactions: prevention and control of immune-mediated diseases. [europepmc]
• IL-17-mediated M1/M2 macrophage alteration contributes to pathogenesis of bisphosphonate-related osteonecrosis of the jaws. [europepmc]
• The role of macrophages and dendritic cells in the initiation of inflammation in IBD. [europepmc]
• P-selectin-mediated monocyte-cerebral endothelium adhesive interactions link peripheral organ inflammation to sickness behaviors. [europepmc]
• M2 macrophages activate WNT signaling pathway in epithelial cells: relevance in ulcerative colitis. [europepmc]
• VEGF-C-dependent stimulation of lymphatic function ameliorates experimental inflammatory bowel disease. [europepmc]
• Regulatory immune cells in regulation of intestinal inflammatory response to microbiota. [europepmc]
• Helminth infection promotes colonization resistance via type 2 immunity. [europepmc]
• The Impact of Western Diet and Nutrients on the Microbiota and Immune Response at Mucosal Interfaces. [europepmc]
• Dietary quercetin ameliorates experimental colitis in mouse by remodeling the function of colonic macrophages via a heme oxygenase-1-dependent pathway. [europepmc]
• Stimulator of interferon genes (STING) activation exacerbates experimental colitis in mice. [europepmc]
• Exosomes from mesenchymal stromal cells reduce murine colonic inflammation via a macrophage-dependent mechanism. [europepmc]
• LncRNA PTPRE-AS1 modulates M2 macrophage activation and inflammatory diseases by epigenetic promotion of PTPRE. [europepmc]
• Human interleukin-4-treated regulatory macrophages promote epithelial wound healing and reduce colitis in a mouse model. [europepmc]
• Amelioration of ulcerative colitis via inflammatory regulation by macrophage-biomimetic nanomedicine. [europepmc]
• Gut microbial bile acid metabolite skews macrophage polarization and contributes to high-fat diet-induced colonic inflammation. [europepmc]
• SOD1 suppresses pro-inflammatory immune responses by protecting against oxidative stress in colitis. [europepmc]
• Tiliroside Ameliorates Ulcerative Colitis by Restoring the M1/M2 Macrophage Balance via the HIF-1α/glycolysis Pathway. [europepmc]
• Pathophysiological communication between hepatocytes and non-parenchymal cells in liver injury from NAFLD to liver fibrosis. [europepmc]
• The immunobiology of preterm labor and birth: intra-amniotic inflammation or breakdown of maternal-fetal homeostasis. [europepmc]
• Macrophage polarization in inflammatory bowel disease. [europepmc]