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Fibrin glue as a protective tool for microanastomoses in limb reconstructive surgery

2015/12/15 by Stefan Langer, Thomas A. Schildhauer, Langer, Stefan +7
Medicine · #610 Medical sciences #Fibrinkleber #Freie-Lappen-Plastik #Hemostasis and retained surgical items #Medicine #Mikroanastomose #Mikrochirurgie #Nervenrepair #Reconstructive Surgery and Microvascular Techniques #Sarcoma Diagnosis and Treatment #fibrin glue #free flap #microanastomosis #microsurgery #nerve reconstruction

paper · doi:10.3205/iprs000073

openalex publication_date 2015/12/15 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/19

Abstract

AIM: Fibrin glue becomes a more and more routinely used tool for stabilization of microanastomoses and nerve repair. This paper summarizes the technical properties and advantages of its use in a wide variety of microsurgical contexts, and includes an exemplary limb reconstructive case. PATIENTS AND METHODS: A total of 131 patients who had undergone elective and emergency microsurgery mainly of the limbs were retrospectively analyzed, as was the use of free flaps. RESULTS: The use of fibrin glue allows for proper positioning of anastomoses and repaired nerves. No torsion of the pedicle could be seen. The flap survival rated >94%. The fibrin glue could stay in place in >99%. In the rare case of revision, the fibrin glue could easily be removed without damaging the region of the microanastomosis. CONCLUSION: Fibrin glue should not be used to repair insufficient, i.e., leaking anastomoses, but it does protect the site of anastomosis from tissue and fluid pressure. It prevents the pedickle from torsion and its use facilitates relocation of the microanastomoses in cases of revision surgery.

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