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Achieving Analytical and Cellular Control in Confined Spaces and Continuous Flow

2018/01/10 by Sabeth Verpoorte, Verpoorte, Sabeth
Biochemistry, Genetics and Molecular Biology · Physics and Astronomy · #FOS: Biological sciences #FOS: Physical sciences #Fluid Dynamics (physics.flu-dyn) #Other Quantitative Biology (q-bio.OT) #physics.flu-dyn #q-bio.OT

paper · pdf · doi:10.48550/arxiv.1802.05605

Nobel Symposium 162, Stockholm, Sweden, 2017 arXiv:1712.08369v1 report-id: Nobel162/2017/16

arxiv created 2018/01/10 · arxiv updated 2018/02/16

Abstract

Sabeth Verpoorte is professor at the University of Groningen. In this contribution she describes the development of a microfluidic incubation system for drug metabolism studies using a "top-down" precision-cut tissue slice model. She also outlines a fundamental particle separation concept, which relies on the generation of controlled bi-directional flow in microchannels having variable cross-sectional dimensions, by opposing pressure-driven and electrokinetic flows.

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