Mechanical requirements for membrane fission: Common facts from various examples

2009/11/10 by Martin Lenz, Sandrine Morlot, Aurélien Roux · 14 citations
Biochemistry, Genetics and Molecular Biology · Engineering · #Lipid Membrane Structure and Behavior #Cellular transport and secretion #Nanopore and Nanochannel Transport Studies

paper · doi:10.1016/j.febslet.2009.11.012

Abstract

Membrane fission is the last step of membrane carrier formation. As fusion, it is a very common process in eukaryotic cells, and participates in the integrity and specificity of organelles. Although many proteins have been isolated to participate in the various membrane fission reactions, we are far from understanding how membrane fission is mechanically triggered. Here we aim at reviewing the well-described examples of dynamin and lipid phase separation, and try to extract the essential requirements for fission. Then, we survey the recent knowledge obtained on other fission reactions, analyzing the similarities and differences with previous examples.

Cited by

• Components of the CtBP1/BARS-dependent fission machinery
• Sorting nexins provide diversity for retromer-dependent trafficking events. [europepmc]
• Mechanics of dynamin-mediated membrane fission. [europepmc]
• Defining the morphology and mechanism of the hemoglobin transport pathway in Plasmodium falciparum-infected erythrocytes. [europepmc]
• Targeting Bacterial Cardiolipin Enriched Microdomains: An Antimicrobial Strategy Used by Amphiphilic Aminoglycoside Antibiotics. [europepmc]
• The Effects of Intra-membrane Viscosity on Lipid Membrane Morphology: Complete Analytical Solution. [europepmc]
• Ectopic Neo-Formed Intracellular Membranes in Escherichia coli : A Response to Membrane Protein-Induced Stress Involving Membrane Curvature and Domains. [europepmc]
• Deformation analysis of lipid membranes subjected to general forms of intra-membrane viscous flow and interactions with an elliptical-cross-section substrate. [europepmc]
• Keeping in touch with the membrane; protein- and lipid-mediated confinement of caveolae to the cell surface. [europepmc]
• Membrane constriction and thinning by sequential ESCRT-III polymerization. [europepmc]
• Lipid accumulation controls the balance between surface connection and scission of caveolae. [europepmc]
• Physical Constraints and Forces Involved in Phagocytosis. [europepmc]
• Brominated lipid probes expose structural asymmetries in constricted membranes. [europepmc]
• A Quarter Century of EHD Protein Research: From Endosomal Recycling to Ciliopathies. [europepmc]

Related

• Phosphatidic acid in membrane rearrangements
• Kinetic Pathway and Micromechanics of Vesicle Fusion/Fission
• Mechanical force induces mitochondrial fission
• Fission of charged alanine dipeptides
• Dynamin recruitment by clathrin coats: a physical step?