Differential effects and underlying mechanisms of voluntary, forced, and combined exercise on ameliorating Alzheimer's disease pathophenotypes

2026/03/11 by Wanyi Li, W.Q. Li, Shiyu Chen +11
Neuroscience · Medicine · #Neurogenesis and neuroplasticity mechanisms #Alzheimer's disease research and treatments #Dementia and Cognitive Impairment Research

paper · doi:10.1016/j.expneurol.2026.115731

Citations

• Long-term voluntary exercise inhibited AGE/RAGE and microglial activation and reduced the loss of dendritic spines in the hippocampi of APP/PS1 transgenic mice