Dexmedetomidine enhances Mitophagy via PINK1 to alleviate hippocampal neuronal Pyroptosis and improve postoperative cognitive dysfunction in elderly rat

2024/05/31 by Yayu Chen, Gen Wei, Xiaojin Feng +2 · 6 citations
Medicine · Neuroscience · #Intensive Care Unit Cognitive Disorders #Anesthesia and Neurotoxicity Research

paper · doi:10.1016/j.expneurol.2024.114842

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• Bibliometric Analysis of Neuroinflammation and Postoperative Cognitive Dysfunction
• Effects of dexmedetomidine on early postoperative cognitive function and postoperative inflammatory response: a systematic review and network meta-analysis. [europepmc]
• Mitophagy-associated programmed neuronal death and neuroinflammation. [europepmc]
• Bibliometric Analysis of Neuroinflammation and Postoperative Cognitive Dysfunction. [europepmc]
• Esketamine ameliorates postoperative cognitive dysfunction aggravated by preoperative acute sleep deprivation in aged mice via the TLR4/NF-κB pathway. [europepmc]
• The neuroprotective effects of Dexmedetomidine: key mechanisms focusing on neuronal programmed cell death. [europepmc]