Activating toll-like receptor 4 after traumatic brain injury inhibits neuroinflammation and the accelerated development of seizures in rats

2022/08/12 by Mozhdeh Radpour, Samira Choopani, Hamid Gholami Pourbadie +1 · 19 citations
Immunology and Microbiology · Medicine · #Agonist #Anesthesia #Endocrinology #Epileptogenesis #Hippocampus #Immune Response and Inflammation #Inflammation #Internal medicine #Medicine #Microglia #Neonatal and fetal brain pathology #Neuroinflammation #Neuroprotection #Pharmacology #Receptor #TLR4 #Traumatic Brain Injury and Neurovascular Disturbances #Traumatic brain injury

paper · doi:10.1016/j.expneurol.2022.114202

published in Experimental Neurology 357, 114202 (Elsevier BV)

openalex publication_date 2022/08/12 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/29

Citations

• Modification of seizure activity by electrical stimulation: II. Motor seizure
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• Administration of monophosphoryl lipid A shortly after traumatic brain injury blocks the following spatial and avoidance memory loss and neuroinflammation. [europepmc]
• Cannabidiol alleviates the inflammatory response in rats with traumatic brain injury through the PGE 2 -EP2-cAMP-PKA signaling pathway. [europepmc]
• Animal Models of Traumatic Brain Injury and Their Relevance in Clinical Settings. [europepmc]
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