Bone morphogenetic proteins mediate cellular response and, together with Noggin, regulate astrocyte differentiation after spinal cord injury

2009/12/12 by Qi Xiao, Yang Du, Wutian Wu +1 · 25 citations
Medicine · Neuroscience · #Spinal Cord Injury Research #Mesenchymal stem cell research #Nerve injury and regeneration

paper · doi:10.1016/j.expneurol.2009.12.003

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• BMP signalling permits population expansion by preventing premature myogenic differentiation in muscle satellite cells. [europepmc]
• The BMP coreceptor RGMb promotes while the endogenous BMP antagonist noggin reduces neurite outgrowth and peripheral nerve regeneration by modulating BMP signaling. [europepmc]
• Different temporal patterns in the expressions of bone morphogenetic proteins and noggin during astroglial scar formation after ischemic stroke. [europepmc]
• Delayed myelination in an intrauterine growth retardation model is mediated by oxidative stress upregulating bone morphogenetic protein 4. [europepmc]
• The multifaceted effects of agmatine on functional recovery after spinal cord injury through Modulations of BMP-2/4/7 expressions in neurons and glial cells. [europepmc]
• MicroRNA dysregulation in spinal cord injury: causes, consequences and therapeutics. [europepmc]
• BMP signaling in axon regeneration. [europepmc]
• Influence of the extracellular matrix on endogenous and transplanted stem cells after brain damage. [europepmc]
• The role of the JAK-STAT pathway in neural stem cells, neural progenitor cells and reactive astrocytes after spinal cord injury. [europepmc]
• Oligodendrocyte Precursor Cells in Spinal Cord Injury: A Review and Update. [europepmc]
• Extracellular cues influencing oligodendrocyte differentiation and (re)myelination. [europepmc]
• Bone Morphogenetic Protein 4 Signalling in Neural Stem and Progenitor Cells during Development and after Injury. [europepmc]
• Efficient and Fast Differentiation of Human Neural Stem Cells from Human Embryonic Stem Cells for Cell Therapy. [europepmc]
• Differentiation of Glial Cells From hiPSCs: Potential Applications in Neurological Diseases and Cell Replacement Therapy. [europepmc]
• Combinatorial lentiviral gene delivery of pro-oligodendrogenic factors for improving myelination of regenerating axons after spinal cord injury. [europepmc]
• Role of bone morphogenetic protein-2/4 in astrocyte activation in neuropathic pain. [europepmc]
• Molecular and histologic outcomes following spinal cord injury in spiny mice, Acomys cahirinus. [europepmc]
• Inhibitors of Myelination and Remyelination, Bone Morphogenetic Proteins, are Upregulated in Human Neurological Disease. [europepmc]
• Bone morphogenic protein signaling in spinal cord injury. [europepmc]
• Activation and Role of Astrocytes in Ischemic Stroke. [europepmc]
• Global hypo-methylation in a proportion of glioblastoma enriched for an astrocytic signature is associated with increased invasion and altered immune landscape. [europepmc]
• Infiltrating circulating monocytes provide an important source of BMP4 at the early stage of spinal cord injury. [europepmc]
• Neural Stem Cells Overexpressing Arginine Decarboxylase Improve Functional Recovery from Spinal Cord Injury in a Mouse Model. [europepmc]
• Mechanism of skeletal muscle atrophy after spinal cord injury: A narrative review. [europepmc]
• Therapeutic potential of placenta-derived stem cells cultivated on noggin-loaded nanochitosan/polypyrrole-alginate conductive scaffold to restore spinal cord injury. [europepmc]