Pathological role of hypoxia in Alzheimer's disease

2009/08/12 by Xin Zhang, Weidong Le · 28 citations
Medicine · Neuroscience · #Alzheimer's disease research and treatments #Neurological Disease Mechanisms and Treatments #Neurological Disorders and Treatments

paper · doi:10.1016/j.expneurol.2009.07.033

Cited by

• Carnosic acid suppresses the production of amyloid-β 1-42 and 1-43 by inducing an α-secretase TACE/ADAM17 in U373MG human astrocytoma cells
• Traumatic Brain Injury, Chronic Traumatic Encephalopathy, and Alzheimer Disease
• The Effects of Hypoxic Hypoxia on Olfactory Sensitivity in Humans
• MicroRNAs in CNS injury: potential roles and therapeutic implications. [europepmc]
• Spatial frequency domain imaging of intrinsic optical property contrast in a mouse model of Alzheimer's disease. [europepmc]
• Label-free oxygen-metabolic photoacoustic microscopy in vivo. [europepmc]
• Thrombin, a mediator of cerebrovascular inflammation in AD and hypoxia. [europepmc]
• Valproic acid reduces neuritic plaque formation and improves learning deficits in APP(Swe) /PS1(A246E) transgenic mice via preventing the prenatal hypoxia-induced down-regulation of neprilysin. [europepmc]
• Photobiomodulation with near infrared light mitigates Alzheimer's disease-related pathology in cerebral cortex - evidence from two transgenic mouse models. [europepmc]
• CD36 upregulation mediated by intranasal LV-NRF2 treatment mitigates hypoxia-induced progression of Alzheimer's-like pathogenesis. [europepmc]
• Successful therapies for Alzheimer's disease: why so many in animal models and none in humans? [europepmc]
• Using the zebrafish model for Alzheimer's disease research. [europepmc]
• Capillary dysfunction: its detection and causative role in dementias and stroke. [europepmc]
• Hypoxia Affects Neprilysin Expression Through Caspase Activation and an APP Intracellular Domain-dependent Mechanism. [europepmc]
• Amyloid Precursor Protein Protects Neuronal Network Function after Hypoxia via Control of Voltage-Gated Calcium Channels. [europepmc]
• Is Beta-Amyloid Accumulation a Cause or Consequence of Alzheimer's Disease? [europepmc]
• Acute Hypoxia Induced an Imbalanced M1/M2 Activation of Microglia through NF-κB Signaling in Alzheimer's Disease Mice and Wild-Type Littermates. [europepmc]
• Anemia is associated with incidence of dementia: a national health screening study in Korea involving 37,900 persons. [europepmc]
• Mouse models of Alzheimer's disease cause rarefaction of pial collaterals and increased severity of ischemic stroke. [europepmc]
• Clusterin in Alzheimer's Disease: Mechanisms, Genetics, and Lessons From Other Pathologies. [europepmc]
• Oxidative inactivation of amyloid beta-degrading proteases by cholesterol-enhanced mitochondrial stress. [europepmc]
• Molecular and Therapeutic Aspects of Hyperbaric Oxygen Therapy in Neurological Conditions. [europepmc]
• The gut microbiome as a target for adjuvant therapy in obstructive sleep apnea. [europepmc]
• Ferulic Acid Ameliorates Alzheimer's Disease-like Pathology and Repairs Cognitive Decline by Preventing Capillary Hypofunction in APP/PS1 Mice. [europepmc]
• Anemia and the Risk of Cognitive Impairment: An Updated Systematic Review and Meta-Analysis. [europepmc]
• Recent development of near-infrared photoacoustic probes based on small-molecule organic dye. [europepmc]
• The potential of hyperbaric oxygen as a therapy for neurodegenerative diseases. [europepmc]
• Oxygen metabolism abnormality and Alzheimer's disease: An update. [europepmc]