Diabetes Reduces Glutamate Oxidation and Glutamine Synthesis in the Retina

2000/06/01 by Erich Lieth, Kathryn F. LaNoue, Kathryn F LaNoue +3 · 27 citations
Neuroscience · Biochemistry, Genetics and Molecular Biology · #Neuroscience and Neuropharmacology Research #Retinal Development and Disorders #Photoreceptor and optogenetics research

paper · doi:10.1006/exer.2000.0840

Citations

• Glial reactivity and impaired glutamate metabolism in short-term experimental diabetic retinopathy. Penn State Retina Research Group.
• Müller cell changes in human diabetic retinopathy.

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• Diabetic retinopathy: loss of neuroretinal adaptation to the diabetic metabolic environment. [europepmc]
• Primary retinal cultures as a tool for modeling diabetic retinopathy: an overview. [europepmc]
• Neuroprotection as a Therapeutic Target for Diabetic Retinopathy. [europepmc]
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• The neurovascular unit and the pathophysiologic basis of diabetic retinopathy. [europepmc]
• Early inner retinal thinning and cardiovascular autonomic dysfunction in type 2 diabetes. [europepmc]
• Nanoparticle-Mediated Delivery of Neuroprotective Substances for the Treatment of Diabetic Retinopathy. [europepmc]
• E2f1 mediates high glucose-induced neuronal death in cultured mouse retinal explants. [europepmc]
• Müller cells and diabetic retinopathy. [europepmc]
• The Role of Microglia in Diabetic Retinopathy: Inflammation, Microvasculature Defects and Neurodegeneration. [europepmc]
• Plasma glutamine and glutamic acid are potential biomarkers for predicting diabetic retinopathy. [europepmc]
• Retinal Neurodegeneration as an Early Manifestation of Diabetic Eye Disease and Potential Neuroprotective Therapies. [europepmc]
• High Glucose-Induced TRPC6 Channel Activation Decreases Glutamate Uptake in Rat Retinal Müller Cells. [europepmc]
• Treatment of diabetic retinopathy through neuropeptide Y-mediated enhancement of neurovascular microenvironment. [europepmc]
• Proinflammatory cytokines trigger biochemical and neurochemical changes in mouse retinal explants exposed to hyperglycemic conditions. [europepmc]
• Photoreceptor cells and RPE contribute to the development of diabetic retinopathy. [europepmc]
• Metabolic Dysregulation and Neurovascular Dysfunction in Diabetic Retinopathy. [europepmc]
• Contribution of Müller Cells in the Diabetic Retinopathy Development: Focus on Oxidative Stress and Inflammation. [europepmc]
• High glutamine suppresses osteogenesis through mTORC1-mediated inhibition of the mTORC2/AKT-473/RUNX2 axis. [europepmc]
• Serum Untargeted Metabolomics Reveal Potential Biomarkers of Progression of Diabetic Retinopathy in Asians. [europepmc]
• Interpretable machine learning-derived nomogram model for early detection of diabetic retinopathy in type 2 diabetes mellitus: a widely targeted metabolomics study. [europepmc]
• The glucocorticoid receptor as a master regulator of the Müller cell response to diabetic conditions in mice. [europepmc]