Measures of hydroxymethylation

2017/08/16 by Slynko, Alla, Benner, Axel
#Applications (stat.AP) #FOS: Biological sciences #FOS: Computer and information sciences #Genomics (q-bio.GN) #Quantitative Methods (q-bio.QM)

paper · doi:10.48550/arxiv.1708.04819

Abstract

Hydroxymethylcytosine (5hmC) methylation is known to be a possible epigenetic mark impacting genome stability. In this paper, we address the existing 5hmC measure Δβ and discuss its properties both analytically and empirically on real data. Then we introduce several alternative hydroxymethylation measures and compare their properties with those of Δβ. All results will be illustrated by means of real data analyses.

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