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Forbidden Science: Dual-Use AI Challenge Benchmark and Scientific Refusal Tests

2025/02/08 by David Noever, Noever, David, Forrest McKee +1
Computer Science · #Artificial Intelligence (cs.AI) #Computation and Language (cs.CL) #Explainable Artificial Intelligence (XAI) #FOS: Computer and information sciences

paper · pdf · doi:10.48550/arxiv.2502.06867

openalex publication_date 2025/02/08 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

The development of robust safety benchmarks for large language models requires open, reproducible datasets that can measure both appropriate refusal of harmful content and potential over-restriction of legitimate scientific discourse. We present an open-source dataset and testing framework for evaluating LLM safety mechanisms across mainly controlled substance queries, analyzing four major models' responses to systematically varied prompts. Our results reveal distinct safety profiles: Claude-3.5-sonnet demonstrated the most conservative approach with 73% refusals and 27% allowances, while Mistral attempted to answer 100% of queries. GPT-3.5-turbo showed moderate restriction with 10% refusals and 90% allowances, and Grok-2 registered 20% refusals and 80% allowances. Testing prompt variation strategies revealed decreasing response consistency, from 85% with single prompts to 65% with five variations. This publicly available benchmark enables systematic evaluation of the critical balance between necessary safety restrictions and potential over-censorship of legitimate scientific inquiry, while providing a foundation for measuring progress in AI safety implementation. Chain-of-thought analysis reveals potential vulnerabilities in safety mechanisms, highlighting the complexity of implementing robust safeguards without unduly restricting desirable and valid scientific discourse.

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