Telomere Shortening Is Associated with Cell Division in Vitro and in Vivo

1995/09/01 by Richard C. Allsopp, Richard Allsopp, Edwin Chang +6 · 26 citations
Medicine · Biochemistry, Genetics and Molecular Biology · #Telomeres, Telomerase, and Senescence #Genetics, Aging, and Longevity in Model Organisms #DNA Repair Mechanisms

paper · doi:10.1006/excr.1995.1306

Cited by

• Telomere length inheritance and aging
• Characterisation of telomerase immortalised normal human oesophageal squamous cells. [europepmc]
• Telomere shortening impairs organ regeneration by inhibiting cell cycle re-entry of a subpopulation of cells. [europepmc]
• Normal and leukemic hematopoiesis: are leukemias a stem cell disorder or a reacquisition of stem cell characteristics? [europepmc]
• HDACs and the senescent phenotype of WI-38 cells. [europepmc]
• Telomere restoration and extension of proliferative lifespan in dyskeratosis congenita fibroblasts. [europepmc]
• Expression of p16(INK4a) in peripheral blood T-cells is a biomarker of human aging. [europepmc]
• Proliferative defects in dyskeratosis congenita skin keratinocytes are corrected by expression of the telomerase reverse transcriptase, TERT, or by activation of endogenous telomerase through expression of papillomavirus E6/E7 or the telomerase RNA component, TERC. [europepmc]
• Bladder cancer in the elderly. [europepmc]
• MnSOD activity regulates hydroxytyrosol-induced extension of chronological lifespan. [europepmc]
• Satellite cells senescence in limb muscle of severe patients with COPD. [europepmc]
• Aging, cellular senescence, and cancer. [europepmc]
• Senescence and the pro-tumorigenic stroma. [europepmc]
• Telomere shortening in neurological disorders: an abundance of unanswered questions. [europepmc]
• On being the right size: increased body size is associated with reduced telomere length under natural conditions. [europepmc]
• Somatic growth and telomere dynamics in vertebrates: relationships, mechanisms and consequences. [europepmc]
• ATRX loss induces multiple hallmarks of the alternative lengthening of telomeres (ALT) phenotype in human glioma cell lines in a cell line-specific manner. [europepmc]
• A prospect of cell immortalization combined with matrix microenvironmental optimization strategy for tissue engineering and regeneration. [europepmc]
• Strand break-induced replication fork collapse leads to C-circles, C-overhangs and telomeric recombination. [europepmc]
• Alternative lengthening of telomeres (ALT) influences survival in soft tissue sarcomas: a systematic review with meta-analysis. [europepmc]
• Telomere length heterogeneity in ALT cells is maintained by PML-dependent localization of the BTR complex to telomeres. [europepmc]
• Telomeres and Telomerase in the Development of Liver Cancer. [europepmc]
• The Paradoxical Role of Cellular Senescence in Cancer. [europepmc]
• Mechanisms of Hydroxyurea-Induced Cellular Senescence: An Oxidative Stress Connection? [europepmc]
• Metabolic Alterations in Cellular Senescence: The Role of Citrate in Ageing and Age-Related Disease. [europepmc]
• "Bone-SASP" in Skeletal Aging. [europepmc]