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Computer algebra in systems biology

2007/12/27 by Reinhard Laubenbacher, Bernd Sturmfels, Laubenbacher, Reinhard +1 · 1 citation
Biochemistry, Genetics and Molecular Biology · Computer Science · #Bioinformatics and Genomic Networks #Gene Regulatory Network Analysis #Microbial Metabolic Engineering and Bioproduction #cs.SC #q-bio.MN #q-bio.QM

paper · pdf · doi:10.48550/arxiv.0712.4248

to appear in American Mathematical Monthly

arxiv created 2008/12/19 · arxiv updated 2009/12/01

Abstract

Systems biology focuses on the study of entire biological systems rather than on their individual components. With the emergence of high-throughput data generation technologies for molecular biology and the development of advanced mathematical modeling techniques, this field promises to provide important new insights. At the same time, with the availability of increasingly powerful computers, computer algebra has developed into a useful tool for many applications. This article illustrates the use of computer algebra in systems biology by way of a well-known gene regulatory network, the Lac Operon in the bacterium E. coli.

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