2025/08/16 by Venkatesan, Eswaradass Prasanna, Balakrishnan, Ramasamy, Ramadoss, Kalidoss +1
#Seizure #vasculopathy #vertebrobasilar dolichoectasia
paper · doi:10.82235/wajr.vol24no1.356
Vertebrobasilar dolichoectasia (VBD) is an uncommon vasculopathy which causes enlargement, tortuosity, or elongation of vertebral and basilar arteries. It is also called dilative arteriopathy. It is a rare anomaly with an incidence of 0.06%–5.8%. Posterior circulation arteries are more commonly affected than anterior circulation arteries. More than 40% of patients with VBD are asymptomatic. It may also present as ischemic stroke, hemorrhagic stroke, compression of cranial nerves and brainstem. VBD can be due to either atherosclerosis or congenital abnormalities such as Marfan’s syndrome, Ehlers–Danlos syndrome, and Fabry’s disease. Here, we describe a case of a 60-year–old male who presented with an episode of generalized seizure. His metabolic workup was negative for seizure. As a part of evaluation, he underwent computed tomography (CT) scan of brain and magnetic resonance imaging of the brain with magnetic resonance angiogram (MRA). His CT/MRA revealed VBD. He was treated with phenytoin and made a good recovery. VBD presenting as stroke is well known in literature, but here we report a rare case of VBD presenting as seizure.