2024/09/26 by Souvik Sadhukhan, Chandan Dasgupta, Sadhukhan, Souvik +3 · 2 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Engineering · #Biological Physics (physics.bio-ph) #FOS: Physical sciences #Lipid Membrane Structure and Behavior #Molecular Communication and Nanonetworks #Soft Condensed Matter (cond-mat.soft) #thermodynamics and calorimetric analyses
paper · pdf · doi:10.48550/arxiv.2409.17816
openalex publication_date 2024/09/26 · openalex created_date 2024/10/27 · openalex updated_date 2026/08/01
Activity-mediated unjamming of a confluent glassy system is crucial for several biological processes, such as embryogenesis and cancer metastasis. During these processes, the cells progressively change their junction properties, characterized by an interaction parameter p0, and become motile. Here, we study the effect of nonequilibrium active fluctuations, in the form of self-propulsion, on the glassy dynamics in a confluent system. We simulate the active Vertex model and use the analytical mode-coupling theory (MCT) to show that the nature of the transition in the presence of activity remains similar to that in a thermal system where the fluctuations are temperature-like. The agreement of the simulation results with the MCT predictions demonstrates that the structure-dynamics feedback mechanism controls the relaxation dynamics. In addition, we present the first computation of a dynamic length scale, ξd, in confluent systems using finite-size scaling, and show that the growing relaxation time exhibita a power-law dependence on ξd. Furthermore, unlike particulate glasses, the static length that governs the finite-size scaling of the relaxation time is proportional to ξd, revealing the unique nature of the glassy dynamics in confluent systems.