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4D Deep Learning for Multiple Sclerosis Lesion Activity Segmentation

2020/04/20 by Gessert, Nils, Bengs, Marcel, Krüger, Julia +5
#Computer Vision and Pattern Recognition (cs.CV) #FOS: Biological sciences #FOS: Computer and information sciences #FOS: Electrical engineering #Image and Video Processing (eess.IV) #Quantitative Methods (q-bio.QM) #electronic engineering #information engineering

paper · doi:10.48550/arxiv.2004.09216

Abstract

Multiple sclerosis lesion activity segmentation is the task of detecting new and enlarging lesions that appeared between a baseline and a follow-up brain MRI scan. While deep learning methods for single-scan lesion segmentation are common, deep learning approaches for lesion activity have only been proposed recently. Here, a two-path architecture processes two 3D MRI volumes from two time points. In this work, we investigate whether extending this problem to full 4D deep learning using a history of MRI volumes and thus an extended baseline can improve performance. For this purpose, we design a recurrent multi-encoder-decoder architecture for processing 4D data. We find that adding more temporal information is beneficial and our proposed architecture outperforms previous approaches with a lesion-wise true positive rate of 0.84 at a lesion-wise false positive rate of 0.19.

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