Head organizer: Cerberus and IGF cooperate in brain induction in Xenopus embryos

2023/12/16 by Yagmur Azbazdar, Edgar M. Pera, Edward M. De Robertis · 1 voice · 1 citation
Biochemistry, Genetics and Molecular Biology · Neuroscience · #Anatomy #Axon Guidance and Neuronal Signaling #Biology #Cell biology #Cell culture #Ectopic expression #Embryo #Embryogenesis #Endocrinology #Genetics #Hedgehog Signaling Pathway Studies #Internal medicine #Neural development #Neurogenesis and neuroplasticity mechanisms #Neuroscience #Notochord #Signal transduction #Wnt signaling pathway #Xenopus

paper · doi:10.1016/j.cdev.2023.203897

openalex publication_date 2023/12/16 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/22

Cited by

• Functional attributes of the anterior mesendoderm in patterning the anterior neural structures during head formation in the mouse

Discussions

• A very curious paper from the De Robertis lab shows how Cerberus - a growth factor that inhibits Wnt signalling, and IGF - a growth factor that activates MAPK signalling, can synergistically induce a [bsky, 24 points, 0 comments]