2002/06/11 by William A. Hercules, William A Hercules, James Lindesay +4
Biochemistry, Genetics and Molecular Biology · Engineering · Physics and Astronomy · #Biological Physics (physics.bio-ph) #Electrohydrodynamics and Fluid Dynamics #FOS: Biological sciences #FOS: Physical sciences #Microbial Inactivation Methods #Microfluidic and Bio-sensing Technologies #Quantitative Methods (q-bio.QM) #physics.bio-ph #q-bio.QM
paper · pdf · doi:10.48550/arxiv.physics/0206027
arxiv created 2002/06/11 · openalex publication_date 2002/06/11 · arxiv updated 2009/12/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
Electroporation of biological cell membranes is a phenomena that occurs almost universally at a transmembrane potential of approximately 1000 mV. Theories of pore formation have been proposed based on electrocompression (Crowley 1972, Malderelli and Steebe 1992), local membrane defects (Abidor and Chizdhmazdev 1979, Weaver and Mintzer 1981, Sugar 1981), and Statistical models were proposed by (Sowers and Lieber 1986). However, these theories do not in general derive the form of the electric field within the pore. In this paper, we present a view that is useful in describing the biological membrane. We also derive an approximate functional form for the electric field in the region of a pore formed in the membrane.