2026/01/06 by Tobias Baril, Daniel Croll · 1 voice
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #Chromosomal and Genetic Variations #Genomics and Phylogenetic Studies #Genome Rearrangement Algorithms
paper · doi:10.1093/nargab/lqag026
Transposable elements (TEs) are found in nearly all eukaryotic genomes. Despite significant advances in the sequencing of genomes, TE resources remain sparse, leading to a lack of traceability, reproducibility, and duplication of effort when annotating TEs. Here, we focus on the fungal kingdom and present MycoMobilome, a database of TE consensus sequences computationally curated using a set of 4309 genomes covering all major clades. The initial database contains 586 441 consensus sequences after filtering to remove putative host genes and low-quality consensus sequences. We provide a consistent naming convention to surface information on the confidence in the classification, including potential conflicting open reading frame functions, along with metadata to enable evaluation of TEs of interest and to determine whether further curation work is required on a case-by-case basis. Finally, we provide guidelines for community contributions and encourage researchers to deposit new or curated sequences, which will be incorporated into future MycoMobilome releases.