Human monoclonal antibodies targeting A35 protect from death caused by mpox

2025/08/26 by Raianna F. Fantin, Meng Yuan, Seok-Chan Park +39 · 1 voice · 9 citations
Immunology and Microbiology · Biochemistry, Genetics and Molecular Biology · #Poxvirus research and outbreaks #Bacillus and Francisella bacterial research #vaccines and immunoinformatics approaches

paper · pdf · doi:10.1016/j.cell.2025.08.004

Citations

• Phasercrystallographic software

Cited by

• ABConformer: Physics-inspired Sliding Attention for Antibody-Antigen Interface Prediction
• Comparative humoral profiles in mpox cases, survivors, and vaccinated individuals reveal correlates of protection against MPXV. [europepmc]
• Potent neutralization by antibodies targeting the MPXV A28 protein. [europepmc]
• An improved and high-throughput mpox virus microneutralization assay. [europepmc]
• Therapeutic Innovations for Monkeypox Inhibition. [europepmc]
• Plant-based production and characterization of monoclonal antibodies targeting extracellular enveloped proteins of the Mpox Virus. [europepmc]
• Recent advances in Mpox across innate immunity, evasion, and clinical outcomes. [europepmc]
• Efficacy and Safety of Messenger RNA Vaccines. [europepmc]
• Discovery and Structural Characterization of a Highly Protective Neutralizing Antibody Targeting the Mpox Virus A35R Protein [europepmc]

Discussions

• 🚨New Paper in Cell 🧵🔎 Happy to share our work led by the @camilahcoelho.bsky.social, on mAbs against mpox. We were very excited (and lucky!) to contribute to this collab. effort. 🦠“Human monocl [bsky, 26 points, 1 comments]