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Anisotropic Hybrid Networks for liver tumor segmentation with uncertainty quantification

2023/08/23 by Benjamin Lambert, Lambert, Benjamin, Pauline Roca +7
Computer Science · Medicine · #AI in cancer detection #Computer Vision and Pattern Recognition (cs.CV) #FOS: Biological sciences #FOS: Computer and information sciences #FOS: Electrical engineering #Image and Video Processing (eess.IV) #Machine Learning (cs.LG) #Medical Image Segmentation Techniques #Quantitative Methods (q-bio.QM) #Radiomics and Machine Learning in Medical Imaging #electronic engineering #information engineering

paper · pdf · doi:10.48550/arxiv.2308.11969

openalex publication_date 2023/08/23 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

The burden of liver tumors is important, ranking as the fourth leading cause of cancer mortality. In case of hepatocellular carcinoma (HCC), the delineation of liver and tumor on contrast-enhanced magnetic resonance imaging (CE-MRI) is performed to guide the treatment strategy. As this task is time-consuming, needs high expertise and could be subject to inter-observer variability there is a strong need for automatic tools. However, challenges arise from the lack of available training data, as well as the high variability in terms of image resolution and MRI sequence. In this work we propose to compare two different pipelines based on anisotropic models to obtain the segmentation of the liver and tumors. The first pipeline corresponds to a baseline multi-class model that performs the simultaneous segmentation of the liver and tumor classes. In the second approach, we train two distinct binary models, one segmenting the liver only and the other the tumors. Our results show that both pipelines exhibit different strengths and weaknesses. Moreover we propose an uncertainty quantification strategy allowing the identification of potential false positive tumor lesions. Both solutions were submitted to the MICCAI 2023 Atlas challenge regarding liver and tumor segmentation.

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