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Exploring Multimodal Approaches for Alzheimer's Disease Detection Using Patient Speech Transcript and Audio Data

2023/07/05 by Hongmin Cai, Xiaoke Huang, Cai, Hongmin +19
Health Professions · Neuroscience · Psychology · #Artificial Intelligence (cs.AI) #Artificial Intelligence in Healthcare #Audio and Speech Processing (eess.AS) #Brain Tumor Detection and Classification #FOS: Computer and information sciences #FOS: Electrical engineering #Mental Health via Writing #Sound (cs.SD) #electronic engineering #information engineering

paper · pdf · doi:10.48550/arxiv.2307.02514

openalex publication_date 2023/07/05 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

Alzheimer's disease (AD) is a common form of dementia that severely impacts patient health. As AD impairs the patient's language understanding and expression ability, the speech of AD patients can serve as an indicator of this disease. This study investigates various methods for detecting AD using patients' speech and transcripts data from the DementiaBank Pitt database. The proposed approach involves pre-trained language models and Graph Neural Network (GNN) that constructs a graph from the speech transcript, and extracts features using GNN for AD detection. Data augmentation techniques, including synonym replacement, GPT-based augmenter, and so on, were used to address the small dataset size. Audio data was also introduced, and WavLM model was used to extract audio features. These features were then fused with text features using various methods. Finally, a contrastive learning approach was attempted by converting speech transcripts back to audio and using it for contrastive learning with the original audio. We conducted intensive experiments and analysis on the above methods. Our findings shed light on the challenges and potential solutions in AD detection using speech and audio data.

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