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Chitosan-based biomaterials for tissue engineering

2013/01/23 by Florence Croisier, Christine Jérôme · 28 citations
Materials Science · #Electrospun Nanofibers in Biomedical Applications #Polymer Surface Interaction Studies #Nanocomposite Films for Food Packaging

paper · doi:10.1016/j.eurpolymj.2012.12.009

Abstract

Derived from chitin, chitosan is a unique biopolymer that exhibits outstanding properties, beside biocompatibility and biodegradability. Most of these peculiar properties arise from the presence of primary amines along the chitosan backbone. As a consequence, this polysaccharide is a relevant candidate in the field of biomaterials, especially for tissue engineering. The current article highlights the preparation and properties of innovative chitosan-based biomaterials, with respect to their future applications. The use of chitosan in 3D-scaffolds – as gels and sponges – and in 2D-scaffolds – as films and fibers – is discussed, with a special focus on wound healing application.

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