Mechanisms underlying paclitaxel-induced neuropathic pain: Channels, inflammation and immune regulations

2022/09/17 by Yuhao Xu, Zongsheng Jiang, Xiaowei Chen · 25 citations
Medicine · #Pain Mechanisms and Treatments #Cancer Treatment and Pharmacology #Peripheral Neuropathies and Disorders

paper · doi:10.1016/j.ejphar.2022.175288

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• Naturally Inspired Molecules for Neuropathic Pain Inhibition-Effect of Mirogabalin and Cebranopadol on Mechanical and Thermal Nociceptive Threshold in Mice. [europepmc]
• Preclinical research in paclitaxel-induced neuropathic pain: a systematic review. [europepmc]
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• The Serotonin-Mediated Anti-Allodynic Effect of Yokukansan on Paclitaxel-Induced Neuropathic Pain. [europepmc]
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• Roles of Thermosensitive Transient Receptor Channels TRPV1 and TRPM8 in Paclitaxel-Induced Peripheral Neuropathic Pain. [europepmc]
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• Degenerative and regenerative peripheral processes are associated with persistent painful chemotherapy-induced neuropathies in males and females. [europepmc]
• Targeting DKK1 enhances the antitumor activity of paclitaxel and alleviates chemotherapy-induced peripheral neuropathy in breast cancer. [europepmc]
• The dual role of TRPV1 in peripheral neuropathic pain: pain switches caused by its sensitization or desensitization. [europepmc]
• Lidocaine Enhanced Antitumor Efficacy and Relieved Chemotherapy-Induced Hyperalgesia in Mice with Metastatic Gastric Cancer. [europepmc]
• Mechanistic study of modulating mitochondrial fission and fusion to ameliorate neuropathic pain in mice. [europepmc]
• Effect of glucagon-like peptide-1 receptor agonist on paclitaxel induced neurotoxicity in dorsal root ganglion neuronal cells in vitro . [europepmc]
• Ozone Treatment in the Management of Chemotherapy-Induced Peripheral Neuropathy: A Review of Rationale and Research Directions. [europepmc]
• Glial Activation Enhances Spinal TRPV1 Receptor Sensitivity in a Paclitaxel Model of Neuropathic Pain. [europepmc]
• The mechanisms of specialized pro-resolving mediators in pain relief: neuro-immune and neuroglial regulations. [europepmc]
• Research on paclitaxel in chemotherapy-induced neuropathic pain: a bibliometric analysis integrating multiple databases. [europepmc]
• Prophylactic Effect of Echinacoside on PIPN by Inhibiting Spinal Neuroinflammation and Exerting Neuroprotective Effects. [europepmc]
• Strain-dependent neuronal disposition and toxicity of paclitaxel in mice. [europepmc]