Protocatechualdehyde prevents methylglyoxal-induced mitochondrial dysfunction and AGEs-RAGE axis activation in Human lens epithelial cells

2014/06/12 by Yuehua Wang, Yue-Hua Wang, Yu-Pei Han +6 · 10 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Advanced Glycation End Products research #Connexins and lens biology #Natural Antidiabetic Agents Studies

paper · doi:10.1016/j.ejphar.2014.04.045

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• Echinacoside Protects against 6-Hydroxydopamine-Induced Mitochondrial Dysfunction and Inflammatory Responses in PC12 Cells via Reducing ROS Production. [europepmc]
• Glyoxalases in Urological Malignancies. [europepmc]
• Enhanced Antioxidant Activity of Bioactives in Colored Grains by Nano-Carriers in Human Lens Epithelial Cells. [europepmc]
• Biosynthesis, Chemistry, and Pharmacology of Polyphenols from Chinese Salvia Species: A Review. [europepmc]
• 5-Bromoprotocatechualdehyde Combats against Palmitate Toxicity by Inhibiting Parkin Degradation and Reducing ROS-Induced Mitochondrial Damage in Pancreatic β-Cells. [europepmc]
• Protocatechualdehyde restores endothelial dysfunction in streptozotocin-induced diabetic rats. [europepmc]
• The m 6 A Methyltransferase METTL3 Ameliorates Methylglyoxal-Induced Impairment of Insulin Secretion in Pancreatic β Cells by Regulating MafA Expression. [europepmc]
• Ishophloroglucin A Isolated from Ishige okamurae Protects Glomerular Cells from Methylglyoxal-Induced Diacarbonyl Stress and Inhibits the Pathogenesis of Diabetic Nephropathy. [europepmc]
• Protocatechualdehyde attenuates oxidative stress in diabetic cataract via GLO1-mediated inhibition of AGE/RAGE glycosylation. [europepmc]