A novel Zebrafish model of Alzheimer's disease by Aluminium chloride; involving nitro-oxidative stress, neuroinflammation and cholinergic pathway

2024/01/14 by Abhishek P.R. Nadiga, Abhishek P. R. Nadiga, Suman +1 · 45 citations
Biochemistry, Genetics and Molecular Biology · Medicine · Neuroscience · #Alzheimer's disease #Alzheimer's disease research and treatments #Amyloid beta #Biochemistry #Biology #Central nervous system #Cholinergic #Disease #Endocrinology #Gene #Internal medicine #Medicine #Neuroinflammation #Neuroinflammation and Neurodegeneration Mechanisms #Neuropathology #Neuroscience #Neurotrophic factors #Oxidative stress #Receptor #Senile plaques #Zebrafish #Zebrafish Biomedical Research Applications

paper · doi:10.1016/j.ejphar.2024.176332

published in European Journal of Pharmacology 965, 176332 (Elsevier BV)

openalex publication_date 2024/01/14 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/26

Citations

• A new and rapid colorimetric determination of acetylcholinesterase activity

Cited by

• Discovery of α-mangostin derivatives as novel PDE4 inhibitors for the treatment of Alzheimer's disease: An artificial intelligence-driven synergized strategy
• Redox Homeostasis, Gut Microbiota, and Epigenetics in Neurodegenerative Diseases: A Systematic Review. [europepmc]
• Identification of a novel pyrrolo[2,3- b ]pyridine compound as a potent glycogen synthase kinase 3β inhibitor for treating Alzheimer's disease. [europepmc]
• Modeling Alzheimer's Disease: A Review of Gene-Modified and Induced Animal Models, Complex Cell Culture Models, and Computational Modeling. [europepmc]
• Beyond Transgenic Mice: Emerging Models and Translational Strategies in Alzheimer's Disease. [europepmc]
• Beyond TLR4 and Its Alternative Lipopolysaccharide (LPS) Sensing Pathways in Zebrafish. [europepmc]
• The Neuroprotective Effects of Cyanidin Derivatives on AlCl 3 -Induced Zebrafish Model of Alzheimer's Disease. [europepmc]
• Comparative neurotoxicity of Bisphenol-A and aluminum chloride in adult zebrafish: Behavioral disruption and region-specific neuropathology under chronic exposure. [europepmc]
• Small-molecule PCSK9 inhibition enhances BBB amyloid-β clearance and suppresses microglial inflammation in Alzheimer's disease models. [europepmc]
• Plant-derived bioactive nutraceuticals mitigate aluminum-mediated neurotoxicity: Elucidated mechanisms and prospects. [europepmc]