Naringenin improves learning and memory in an Alzheimer's disease rat model: Insights into the underlying mechanisms
2015/07/05 by Saeed Ghofrani, Mohammad-Taghi Joghataei, Mohammad Taghi Joghataei +5 · 183 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Neuroscience · Psychology · #Alzheimer's disease research and treatments #Antioxidant #Biochemistry #Chemistry #Cognition #Endocrinology #Estrogen and related hormone effects #Hippocampus #Internal medicine #Malondialdehyde #Medicine #Memory impairment #Menopause: Health Impacts and Treatments #Naringenin #Neuroscience #Oxidative stress #Pharmacology #Psychology #Superoxide dismutase #Water maze
paper · open access · doi:10.1016/j.ejphar.2015.07.001
published in European Journal of Pharmacology 764, 195-201 (Elsevier BV)
openalex publication_date 2015/07/05 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/31
Citations
Cited by
- Trigonelline protects hippocampus against intracerebral Aβ(1–40) as a model of Alzheimer’s disease in the rat: insights into underlying mechanisms
- Naringin and Naringenin: Potential Multi-Target Agents for Alzheimer’s Disease
- Mitochondria and lipid peroxidation in the mechanism of neurodegeneration: Finding ways for prevention
- Effects of acupuncture at HT7 on glucose metabolism in a rat model of Alzheimer's disease: an 18F-FDG-PET study. [europepmc]
- A Systematic Strategy for Discovering a Therapeutic Drug for Alzheimer's Disease and Its Target Molecule. [europepmc]
- Protective Role Of Naringenin Against Aβ 25-35 -Caused Damage via ER and PI3K/Akt-Mediated Pathways. [europepmc]
- The Therapeutic Potential of Naringenin: A Review of Clinical Trials. [europepmc]
- Effects and Underlying Mechanisms of Bioactive Compounds on Type 2 Diabetes Mellitus and Alzheimer's Disease. [europepmc]
- Natural Compounds for Alzheimer's Disease Therapy: A Systematic Review of Preclinical and Clinical Studies. [europepmc]
- On the Neuroprotective Effects of Naringenin: Pharmacological Targets, Signaling Pathways, Molecular Mechanisms, and Clinical Perspective. [europepmc]
- The Nrf2/HO-1 Axis as Targets for Flavanones: Neuroprotection by Pinocembrin, Naringenin, and Eriodictyol. [europepmc]
- Naringenin protects AlCl3/D-galactose induced neurotoxicity in rat model of AD via attenuation of acetylcholinesterase levels and inhibition of oxidative stress. [europepmc]
- Collapsin Response Mediator Proteins: Their Biological Functions and Pathophysiology in Neuronal Development and Regeneration. [europepmc]
- Phenolic Profiles, Antioxidant, and Inhibitory Activities of Kadsura heteroclita (Roxb.) Craib and Kadsura coccinea (Lem.) A.C. Sm. [europepmc]
- Attenuation of Nrf2/Keap1/ARE in Alzheimer's Disease by Plant Secondary Metabolites: A Mechanistic Review. [europepmc]
- Multi-Therapeutic Potential of Naringenin (4',5,7-Trihydroxyflavonone): Experimental Evidence and Mechanisms. [europepmc]
- PERK Pathway and Neurodegenerative Disease: To Inhibit or to Activate? [europepmc]
- Citrus Polyphenols in Brain Health and Disease: Current Perspectives. [europepmc]
- Potential Health Benefits of Plant Food-Derived Bioactive Components: An Overview. [europepmc]
- Acetylcholinesterase Inhibitors in the Treatment of Neurodegenerative Diseases and the Role of Acetylcholinesterase in their Pathogenesis. [europepmc]
- Potential of Sorghum Polyphenols to Prevent and Treat Alzheimer's Disease: A Review Article. [europepmc]
- Naringenin: A Promising Therapeutic Agent against Organ Fibrosis. [europepmc]
- Role of Phytoconstituents as PPAR Agonists: Implications for Neurodegenerative Disorders. [europepmc]
- Establishing an Autonomous Cascaded Artificial Dynamic (AutoCAD) regulation system for improved pathway performance. [europepmc]
- Neuroprotective effect of naringin against cerebellar changes in Alzheimer's disease through modulation of autophagy, oxidative stress and tau expression: An experimental study. [europepmc]
- Non-Enzymatic Antioxidants against Alzheimer's Disease: Prevention, Diagnosis and Therapy. [europepmc]
- Naringin and Naringenin Polyphenols in Neurological Diseases: Understandings from a Therapeutic Viewpoint. [europepmc]
- Naringenin ameliorates amyloid-β pathology and neuroinflammation in Alzheimer's disease. [europepmc]