Induction of CYP3A4 and MDR1 gene expression by baicalin, baicalein, chlorogenic acid, and ginsenoside Rf through constitutive androstane receptor- and pregnane X receptor-mediated pathways

2010/05/25 by Yue Li, Qi Wang, Xiaomin Yao +1 · 10 citations
Pharmacology, Toxicology and Pharmaceutics · Biochemistry, Genetics and Molecular Biology · #Pharmacogenetics and Drug Metabolism #Pharmacological Effects of Natural Compounds #Ginseng Biological Effects and Applications

paper · doi:10.1016/j.ejphar.2010.05.017

Citations

• Ginseng pharmacology

Cited by

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• miR-137 regulates the constitutive androstane receptor and modulates doxorubicin sensitivity in parental and doxorubicin-resistant neuroblastoma cells. [europepmc]
• Ginsenoside Rf inhibits cyclooxygenase-2 induction via peroxisome proliferator-activated receptor gamma in A549 cells. [europepmc]
• Phytochemicals: Potential Lead Molecules for MDR Reversal. [europepmc]
• Herb-drug Interactions in Neuropsychiatric Pharmacotherapy - A Review of Clinically Relevant Findings. [europepmc]
• Baicalin Enhanced Oral Bioavailability of Sorafenib in Rats by Inducing Intestine Absorption. [europepmc]
• Phytochemicals That Interfere With Drug Metabolism and Transport, Modifying Plasma Concentration in Humans and Animals. [europepmc]
• Causative Role of Anoxic Environment in Bacterial Regulation of Human Intestinal Function. [europepmc]
• Chlorogenic acid induces hepatocellular carcinoma cell ferroptosis via PTGS2/AKR1C3/GPX4 axis-mediated reprogramming of arachidonic acid metabolism. [europepmc]
• Research progress on traditional Chinese medicine-assisted immune checkpoint inhibitors therapy for solid tumors. [europepmc]