2025/11/18 by Bhattacharya, Chandrachur, Som, Sibendu
Computer Science · Decision Sciences · #Artificial Intelligence (cs.AI) #Computation and Language (cs.CL) #FOS: Computer and information sciences #Multi-Agent Systems and Negotiation #Multiagent Systems (cs.MA) #Scientific Computing and Data Management #Semantic Web and Ontologies
paper · doi:10.48550/arxiv.2511.14043
openalex publication_date 2025/11/18 · openalex created_date 2025/11/20 · openalex updated_date 2026/07/28
AI Scientific Assistant Core (AISAC) is a transparent, modular multi-agent runtime developed at Argonne National Laboratory to support long-horizon, evidence-grounded scientific reasoning. Rather than proposing new agent algorithms or claiming autonomous scientific discovery, AISAC contributes a governed execution substrate that operationalizes key requirements for deploying agentic AI in scientific practice, including explicit role semantics, budgeted context management, traceable execution, and reproducible interaction with tools and knowledge. AISAC enforces four structural guarantees for scientific reasoning: (1) declarative agent registration with runtime-enforced role semantics and automatic system prompt generation; (2) budgeted orchestration via explicit per-turn context and delegation depth limits; (3) role-aligned memory access across episodic, dialogue, and evidence layers; and (4) trace-driven transparency through persistent execution records and a live event-stream interface. These guarantees are implemented through hybrid persistent memory (SQLite and dual FAISS indices), governed retrieval with agent-scoped RAG, structured tool execution with schema validation, and a configuration-driven bootstrap mechanism that enables project specific extension without modifying the shared core. AISAC is currently deployed across multiple scientific workflows at Argonne, including combustion science, materials research, and energy process safety, demonstrating its use as a reusable substrate for domain-specialized AI scientific assistants.