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ColonCrafter: A Depth Estimation Model for Colonoscopy Videos Using Diffusion Priors

2025/09/16 by Romain Hardy, Tyler M. Berzin, Hardy, Romain +3
Computer Science · Medicine · #Advanced Image and Video Retrieval Techniques #Advanced Vision and Imaging #Artificial Intelligence (cs.AI) #Colorectal Cancer Screening and Detection #Computer Vision and Pattern Recognition (cs.CV) #FOS: Computer and information sciences #Machine Learning (cs.LG)

paper · pdf · doi:10.48550/arxiv.2509.13525

openalex publication_date 2025/09/16 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

Three-dimensional (3D) scene understanding in colonoscopy presents significant challenges that necessitate automated methods for accurate depth estimation. However, existing depth estimation models for endoscopy struggle with temporal consistency across video sequences, limiting their applicability for 3D reconstruction. We present ColonCrafter, a diffusion-based depth estimation model that generates temporally consistent depth maps from monocular colonoscopy videos. Our approach learns robust geometric priors from synthetic colonoscopy sequences to generate temporally consistent depth maps. We also introduce a style transfer technique that preserves geometric structure while adapting real clinical videos to match our synthetic training domain. ColonCrafter achieves state-of-the-art zero-shot performance on the C3VD dataset, outperforming both general-purpose and endoscopy-specific approaches. Although full trajectory 3D reconstruction remains a challenge, we demonstrate clinically relevant applications of ColonCrafter, including 3D point cloud generation and surface coverage assessment.

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