2003/09/03 by David J. Fry, Fry, D., Nathan R. Hutchings +3
Materials Science · Medicine · #Adaptation and Self-Organizing Systems (nlin.AO) #Biological Physics (physics.bio-ph) #Cell Behavior (q-bio.CB) #Chemical Physics (physics.chem-ph) #FOS: Biological sciences #FOS: Physical sciences #Fluid Dynamics (physics.flu-dyn) #Liquid Crystal Research Advancements #Pattern Formation and Solitons (nlin.PS) #Quantitative Methods (q-bio.QM) #Subcellular Processes (q-bio.SC) #Trypanosoma species research and implications
paper · pdf · doi:10.48550/arxiv.physics/0309026
openalex publication_date 2003/09/03 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
Although the auger-like 'swimming' motility of the African trypanosome was described upon its discovery over one hundred years ago, the precise biomechanical and biophysical properties of trypanosome flagellar motion has not been elucidated. In this study, we describe five different modes of flagellar beat/wave patterns in African trypanosomes by microscopically examining the flagellar movements of chemically tethered cells. The dynamic nature of the different beat/wave patterns suggests that flagellar motion in Trypanosoma brucei is a complex mixture of oscillating waves, rigid bends, helical twists and non-linear waves. Interestingly, we have observed soliton-like depression waves along the flagellar membrane, suggesting a nonlinear mechanism for the dynamics of this system. The physical model is inspired by the 2-dimensional elastic dynamics of a beam, and by taking into account uniform distribution of molecular motors torque and nonlinear terms in the curvature.