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From conception to clinical trial: IViST -- the first multi-sensor-based platform for real-time In Vivo dosimetry and Source Tracking in HDR brachytherapy

2020/06/14 by Haydee M. Linares Rosales, Rosales, Haydee M. Linares, Audrey Cantin +7
Engineering · Medicine · Physics and Astronomy · #Advanced Radiotherapy Techniques #Advanced X-ray and CT Imaging #FOS: Physical sciences #Medical Physics (physics.med-ph) #Radiation Therapy and Dosimetry

paper · pdf · doi:10.48550/arxiv.2006.08031

openalex publication_date 2020/06/14 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

This study aims to introduce IViST (In Vivo Source Tracking), a novel multi-sensors dosimetry platform for real-time treatment monitoring in HDR brachytherapy. IViST is a platform that comprises 3 parts: 1) an optimized and characterized multi-point plastic scintillator dosimeter (3 points mPSD; using BCF-60, BCF-12, and BCF-10 scintillators), 2) a compact assembly of photomultiplier tubes (PMTs) coupled to dichroic mirrors and filters for high-sensitivity scintillation light collection, and 3) a Python-based graphical user interface used for system management and signal processing. IViST can simultaneously measure dose, triangulate source position, and measure dwell time. By making 100 000 measurements/s, IViST samples enough data to quickly perform key QA/QC tasks such as identifying wrong individual dwell time or interchanged transfer tubes. By using 3 co-linear sensors and planned information for an implant geometry (from DICOM RT), the platform can also triangulate source position in real-time. A clinical trial is presently on-going using the IViST system.

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