2011/06/15 by Veronica Ines Cacace, Nicolas Montalbetti, Nicolás Montalbetti +10
Biochemistry, Genetics and Molecular Biology · Medicine · Physics and Astronomy · #Biological Physics (physics.bio-ph) #Connexins and lens biology #Corneal Surgery and Treatments #Corneal surgery and disorders #FOS: Physical sciences #Ocular Surface and Contact Lens #Ocular and Laser Science Research #physics.bio-ph
paper · pdf · doi:10.48550/arxiv.1106.3053
17 pages, 4 figures, 1 table
arxiv created 2011/06/15 · openalex publication_date 2011/06/15 · arxiv updated 2011/06/16 · openalex created_date 2022/10/05 · openalex updated_date 2026/07/28
There is evidence that the electrical potential difference of corneal endothelium (TEPD) is related electro-osmotically to fluid transport. Hence, determination of the TEPD would serve as a measure of the fluid movement. The oscillatory nature of the TEPD has been recognized recently using the Fourier transform; the oscillations of the highest amplitude were linked to the operation of electrogenic sodium-bicarbonate cotransporters. However, no time localization of that activity could be obtained with the Fourier methodology utilized. For that reason we now characterize the TEPD using wavelet analysis for the first time in the epithelial physiology field, with the aim to localize in time the variations in TEPD. We find that the high-amplitude oscillations of the TEPD are cyclic, with a period of 4.6 ± 0.4 s in the average (n=4). The wavelet power value at the peak of such oscillations is 1.5 ± 0.1 mV2 Hz in the average (n=4), and is remarkably narrow in its distribution.