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Gradient Hyperalignment for multi-subject fMRI data alignment

2018/07/07 by Tonglin Xu, Xu, Tonglin, Muhammad Yousefnezhad +3
Computer Science · Neuroscience · #Blind Source Separation Techniques #Domain Adaptation and Few-Shot Learning #FOS: Biological sciences #FOS: Computer and information sciences #Functional Brain Connectivity Studies #Machine Learning (cs.LG) #Machine Learning (stat.ML) #Neurons and Cognition (q-bio.NC)

paper · pdf · doi:10.48550/arxiv.1807.02612

openalex publication_date 2018/07/07 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

Multi-subject fMRI data analysis is an interesting and challenging problem in human brain decoding studies. The inherent anatomical and functional variability across subjects make it necessary to do both anatomical and functional alignment before classification analysis. Besides, when it comes to big data, time complexity becomes a problem that cannot be ignored. This paper proposes Gradient Hyperalignment (Gradient-HA) as a gradient-based functional alignment method that is suitable for multi-subject fMRI datasets with large amounts of samples and voxels. The advantage of Gradient-HA is that it can solve independence and high dimension problems by using Independent Component Analysis (ICA) and Stochastic Gradient Ascent (SGA). Validation using multi-classification tasks on big data demonstrates that Gradient-HA method has less time complexity and better or comparable performance compared with other state-of-the-art functional alignment methods.

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