2017/08/25 by Pierre A. Haas, Haas, Pierre A., Stephanie S. M. H. Höhn +7
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · Energy · Engineering · #Advanced Materials and Mechanics #Algal biology and biofuel production #Biocrusts and Microbial Ecology #Biological Physics (physics.bio-ph) #Cellular Mechanics and Interactions #FOS: Biological sciences #FOS: Physical sciences #Soft Condensed Matter (cond-mat.soft) #Tissues and Organs (q-bio.TO)
paper · pdf · doi:10.48550/arxiv.1708.07765
openalex publication_date 2017/08/25 · openalex created_date 2022/10/01 · openalex updated_date 2026/07/28
Many embryonic deformations during development are the global result of local\ncell shape changes and other local active cell sheet deformations.\nMorphogenesis does not only therefore rely on the ability of the tissue to\nproduce these active deformations, but also on the ability to regulate them in\nsuch a way as to overcome the intrinsic variability of and geometric\nconstraints on the tissue. Here, we explore the interplay of regulation and\nvariability in the green alga Volvox, whose spherical embryos turn themselves\ninside out to enable motility. Through a combination of light sheet microscopy\nand theoretical analysis, we quantify the variability of this inversion and\nanalyse its mechanics in detail to show how shape variability arises from a\ncombination of geometry, mechanics, and active regulation.\n