2025/08/22 by Nan wang, wang, Nan, Zhiyi Xia +17 · 1 citation
Biochemistry, Genetics and Molecular Biology · Materials Science · #Advanced Electron Microscopy Techniques and Applications #Computer Vision and Pattern Recognition (cs.CV) #Electron and X-Ray Spectroscopy Techniques #FOS: Computer and information sciences #Machine Learning in Materials Science
paper · pdf · doi:10.48550/arxiv.2508.16239
openalex publication_date 2025/08/22 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
Quantitative microstructural characterization is fundamental to materials science, and electron micrographs (EMs) provide indispensable high-resolution insights. However, progress in deep learning-based analysis of EMs has been hampered by the scarcity of large-scale, expert-annotated public datasets. To address this issue, we introduce EM3M, a large-scale and multimodal dataset for instance-level understanding of EMs. EM3M comprises 5,091 high-quality EMs, approximately 3 million instance segmentation annotations, and image-level textual descriptions with disentangled attributes. The dataset is constructed through a rigorous multi-stage curation and validation pipeline, with comprehensive statistical analyses to ensure reliability and reproducibility. Building upon these curated image-text pairs, we further provide a text-to-image diffusion model that serves as a controllable data augmentation engine, demonstrating that synthetic augmentation consistently improves downstream segmentation performance. To establish a systematic benchmark, we evaluate representative instance segmentation methods on EM3M. Our results reveal that conventional detection-based and query-based methods struggle with the extreme instance densities and textural complexities inherent in EMs. We additionally provide an optimized flow-based baseline to facilitate fair comparison and future research. EM3M Dataset: https://huggingface.co/datasets/UniParser/EM3M, the generative engine Generation: https://huggingface.co/UniParser/EM3M-Gen, and an online demo Segmentation demo: https://www.bohrium.com/apps/uni-aims are publicly available to support future research in automated materials analysis.