Imeglimin Hydrochloride: First Approval

2021/09/01 by Yvette N. Lamb · 14 citations
Medicine · Biochemistry, Genetics and Molecular Biology · #Diabetes Treatment and Management #Pancreatic function and diabetes #Biochemical and Molecular Research

paper · doi:10.1007/s40265-021-01589-9

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• Imeglimin systematic review: a novel therapeutic approach for type 2 diabetes—unveiling benefits on β-cell function, insulin sensitivity, and potential long-term glycaemic control (HbA1c)
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• A Novel Gastrodin Derivative with Neuroprotection Promotes NGF-Mimic Activity by Targeting INSR and ACTN4 to Activate PI3K/Akt Signaling Pathway in PC12 Cells. [europepmc]
• Bioequivalence assessment of imeglimin hydrochloride tablet, a novel glimin-class antidiabetic agent. [europepmc]
• Predictors of glycemic control with imeglimin for type 2 diabetes: Results of machine learning analyses using clinical trial data. [europepmc]
• Stability indicating green HPLC method for Imeglimin hydrochloride determination in pharmaceutical tablets with comprehensive assessment. [europepmc]
• Imeglimin Exerts Anti-Tumor Activity in Multiple Myeloma Through Affecting Energy Metabolism and Downregulating IL-16 Expression. [europepmc]
• Aging-dependent microglial heterogeneity worsens outcomes in models of traumatic brain injury. [europepmc]
• A Novel Ultra-Performance Liquid Chromatography-Electrospray Ionisation-Tandem Mass Spectrometry Method for Quantification of Imeglimin in Human Plasma: Application to a Bioequivalence Study. [europepmc]