Tamoxifen Resistance in Breast Cancer

2001/01/01 by Lambert C. J. Dorssers, Lambert C.J. Dorssers, S. van der Flier +9 · 20 citations
Biochemistry, Genetics and Molecular Biology · Computer Science · #Estrogen and related hormone effects #Computational Drug Discovery Methods #Genomics and Chromatin Dynamics

paper · doi:10.2165/00003495-200161120-00004

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• Structural insights into selective agonist actions of tamoxifen on human estrogen receptor alpha. [europepmc]
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• Cas proteins: dodgy scaffolding in breast cancer. [europepmc]
• Denoising perturbation signatures reveal an actionable AKT-signaling gene module underlying a poor clinical outcome in endocrine-treated ER+ breast cancer. [europepmc]
• Alternative Splicing in Breast Cancer and the Potential Development of Therapeutic Tools. [europepmc]
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• The interaction of p130Cas with PKN3 promotes malignant growth. [europepmc]
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• p130Cas/ BCAR1 and p140Cap/ SRCIN1 Adaptors: The Yin Yang in Breast Cancer? [europepmc]
• High BRCA1 gene expression increases the risk of early distant metastasis in ER + breast cancers. [europepmc]
• Factors Influencing Pharmacokinetics of Tamoxifen in Breast Cancer Patients: A Systematic Review of Population Pharmacokinetic Models. [europepmc]
• The role of mitochondrial/metabolic axis in development of tamoxifen resistance in breast cancer. [europepmc]