Protection against methylglyoxal-derived AGEs by regulation of glyoxalase 1 prevents retinal neuroglial and vasodegenerative pathology

2011/12/05 by A. K. Berner, Andre Berner, Olaf Brouwers +21 · 30 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Advanced Glycation End Products research #Retinal Diseases and Treatments #Chronic Kidney Disease and Diabetes

paper · pdf · doi:10.1007/s00125-011-2393-0

Citations

• Müller cell changes in human diabetic retinopathy.

Cited by

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• Methylglyoxal in Metabolic Disorders: Facts, Myths, and Promises
• The role of methylglyoxal and the glyoxalase system in diabetes and other age-related diseases
• Methylglyoxal and Its Adducts: Induction, Repair, and Association with Disease
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• Methylglyoxal as a new biomarker in patients with septic shock: an observational clinical study. [europepmc]
• Role of the receptor for advanced glycation endproducts (RAGE) in retinal vasodegenerative pathology during diabetes in mice. [europepmc]
• Prevention of protein glycation by natural compounds. [europepmc]
• The protection conferred against ischemia-reperfusion injury in the diabetic brain by N-acetylcysteine is associated with decreased dicarbonyl stress. [europepmc]
• Dicarbonyls and glyoxalase in disease mechanisms and clinical therapeutics. [europepmc]
• The Glyoxalase System and Methylglyoxal-Derived Carbonyl Stress in Sepsis: Glycotoxic Aspects of Sepsis Pathophysiology. [europepmc]
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• Dicarbonyl Stress and Glyoxalase-1 in Skeletal Muscle: Implications for Insulin Resistance and Type 2 Diabetes. [europepmc]
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• Discovery of GLO1 New Related Genes and Pathways by RNA-Seq on A2E-Stressed Retinal Epithelial Cells Could Improve Knowledge on Retinitis Pigmentosa. [europepmc]
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• Glyoxalase System as a Therapeutic Target against Diabetic Retinopathy. [europepmc]
• The Role of Lipoxidation in the Pathogenesis of Diabetic Retinopathy. [europepmc]
• Diabetic Complications and Oxidative Stress: A 20-Year Voyage Back in Time and Back to the Future. [europepmc]
• The Glyoxalase System in Age-Related Diseases: Nutritional Intervention as Anti-Ageing Strategy. [europepmc]
• Normalizing HIF-1α Signaling Improves Cellular Glucose Metabolism and Blocks the Pathological Pathways of Hyperglycemic Damage. [europepmc]
• Emerging Glycation-Based Therapeutics-Glyoxalase 1 Inducers and Glyoxalase 1 Inhibitors. [europepmc]
• Methylglyoxal and Its Adducts: Induction, Repair, and Association with Disease. [europepmc]
• Classification of diabetic retinopathy: Past, present and future. [europepmc]