2013/07/15 by Hayato Tsuda, Tsuda, Hayato, Osamu Narikiyo +1
Biochemistry, Genetics and Molecular Biology · Physics and Astronomy · #Bacterial Genetics and Biotechnology #Biomolecules (q-bio.BM) #FOS: Biological sciences #Origins and Evolution of Life #RNA and protein synthesis mechanisms #Subcellular Processes (q-bio.SC)
paper · pdf · doi:10.48550/arxiv.1307.3857
openalex publication_date 2013/07/15 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
A mechanism of the translation in oligomer world is proposed. The translation is carried out by a minimum cycle, which is sustained by adaptors and helicases, and the first information processing in oligomer world. We expect that such a cycle actually worked in a primitive cell and can be constructed in vitro. By computer simulation we have shown that a proofreading is achieved by the fluctuation in the cell. It is rather paradoxical that the proofreading is effective for the system consisting of molecular machines with low efficiency.