2018/12/25 by Yusei Miura, Miura, Yusei, Tetsuya Sakurai +9
Biochemistry, Genetics and Molecular Biology · Computer Science · Materials Science · #Cell Image Analysis Techniques #Computer Vision and Pattern Recognition (cs.CV) #Enzyme Structure and Function #FOS: Computer and information sciences #Machine Learning in Materials Science #cs.CV
paper · pdf · doi:10.48550/arxiv.1812.10087
7 pages, 16 figures
arxiv created 2018/12/25 · openalex publication_date 2018/12/25 · arxiv updated 2018/12/27 · openalex created_date 2019/01/01 · openalex updated_date 2026/07/28
Recently, deep convolutional neural networks have shown good results for image recognition. In this paper, we use convolutional neural networks with a finder module, which discovers the important region for recognition and extracts that region. We propose applying our method to the recognition of protein crystals for X-ray structural analysis. In this analysis, it is necessary to recognize states of protein crystallization from a large number of images. There are several methods that realize protein crystallization recognition by using convolutional neural networks. In each method, large-scale data sets are required to recognize with high accuracy. In our data set, the number of images is not good enough for training CNN. The amount of data for CNN is a serious issue in various fields. Our method realizes high accuracy recognition with few images by discovering the region where the crystallization drop exists. We compared our crystallization image recognition method with a high precision method using Inception-V3. We demonstrate that our method is effective for crystallization images using several experiments. Our method gained the AUC value that is about 5% higher than the compared method.