2024/12/31 by Saadouli, D., Alaya, N., Ben Mansour, K. +4
#Aniridia #Aniridie #Chirurgie #Congenital glaucoma #Glaucome congénital #Prognosis #Pronostic #Surgery #Therapeutics #Thérapeutique
paper · doi:10.71566/pist-rmp-194775
Introduction : Developmental glaucoma is paediatric glaucoma secondary to developmental abnormalities. It is a heterogeneous group of rare conditions with a wide range of causes and clinical manifestations. He- rein, we aimed to evaluate the clinical outcome of developmental glaucoma. Methods : This was a retrospective study including 54 eyes of 28 patients with developmental glaucoma. De- mographic, clinical and therapeutic data were analyzed retrospectively. In order to identify factors independently associated with severe clinical outcome, we conducted a logistic regression analysis in descending order. Results : The mean age was 114. 36 ± 60 months with a sex ratio of 0. 73. The bilateral rate was 85%. Patients were divided into 4 clinical forms: Peters syndrome , Axenfeld Rieger , Aniridia (6 eyes) and Sturge Weber (4eyes). Visual acuity was below 1/10 in 58% of cases. The mean age of performing the first surgery was 44. 44 ± 30 months. The presence of severe glaucomatous neuropathy (C/D = 0. 8) at the time of diagnosis was an independent risk factor for severe visual impairment and long-term surgical failure. Short and long-term surgical successes were protective factors for low vision. Conclusion : Developmental glaucoma can lead to blindness. The delayed diagnosis was a risk factor for poor vision and surgical failure.