Laser-driven electron source suitable for single-shot Gy-scale irradiation of biological cells at dose-rates exceeding 10¹⁰ Gy/s

2023/09/13 by McAnespie, C. A., Chaudhary, P., Calvin, L. +5
#FOS: Physical sciences #Medical Physics (physics.med-ph) #Plasma Physics (physics.plasm-ph)

paper · doi:10.48550/arxiv.2309.06870

Abstract

We report on the first systematic characterisation of a tuneable laser-driven electron source capable of delivering Gy-scale doses in a duration of 10 - 20 ps, thus reaching unprecedented dose rates in the range of 10¹⁰ - 10¹² Gy/s. Detailed characterisation of the source indicates, in agreement with Monte-Carlo simulations, single-shot delivery of multi-Gy doses per pulse over cm-scale areas, with a high degree of spatial uniformity. The results reported here confirm that a laser-driven source of this kind can be used for systematic studies of the response of biological cells to picosecond-scale radiation at ultra-high dose rates.

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